Don’t despair — Zoloft can help

Don’t despair — Zoloft can help

Zoloft is used to treat a wide range of anxiety and depression-based conditions in adults. All these conditions go beyond the everyday moods of worry and despair. Zoloft helps when the emotional states become more extreme and begin to actively interfere with your ability to live an ordinary life. These include:
• Obsessive-compulsive disorder (OCD) where you might obsessionally repeat behaviour, e.g. wash your hands or ritually clean your home. This is the only situation in which Zoloft can be used to treat children and young adults.
• Panic disorder where you are suddenly overwhelmed by fear or terror.
• Post-traumatic stress disorder where serious injury or death is threatened and this causes an obsessive reaction either in guilt about what happened or fear that it may be about to happen again.
• Social anxiety disorder is an extreme sense that people are judging you which makes you afraid of mixing with others.
• Pre-menstrual dysphoric disorder (PMDD) is an extreme form of pre-menstrual syndrome (PMS) where you feel so sad that you panic easily and may even find things get so on top of you that you consider suicide as an option.

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How does Zoloft work?

Zoloft is a Selective Serotonin Reuptake Inhibitor (SSRI) which increases the amount of serotonin in the brain and helps you to stay calm. Medical scientists believe that serotonin not only affects your mood, but also helps to regulate your body’s temperature, the extent to which you feel pain, and the amount you eat and sleep. Although no-one can give a perfect explanation of how Zoloft works, it has been on the market for seventeen years with clear and continuing support from the medical profession and millions of patients every year who rely on it to keep anxiety and depression at bay.

The Food and Drug Administration directs all manufacturers to place a warning on antidepressants that the use of any SSRI including Zoloft to treat depression in anyone under the age of 25 years may increase the risk of suicide. This reflects research which demonstrates that a person taking an antidepressant is twice as likely to commit suicide as a person with no treatment.

There is also a general problem with SSRIs including Zoloft when it comes to discontinuing the treatment. If you have been taking Zoloft in larger doses over a longer period of time, you will need to discuss strategies with your doctor. About 60% of those who take SSRIs experience withdrawal symptoms.

Zoloft was derived from research which began in the 1970s. Pfizer was experimenting with a norepinephrine reuptake inhibitor but found that it had undesirable side effects. Work then shifted to modify the product to become an SSRI. Zoloft was approved by the Food and Drug Administration (FDA) in 1991. There were questions asked about the quality of the decision, suggesting that the research evidence in support of the product was thin. Nevertheless, Zoloft’s continuing performance has built up a track record of safe and effective treatment among adults. As an exception to the adult-only rule, in 2003, the FDA approved the use of Zoloft for the treatment of OCD in children — this does not apply in the UK. This medication is now out of patent protection and available as a generic. As a result, the price of Zoloft has become very competitive.